Showing profile for Dr Pankaj Singla PhD

Position: Marrie Curie Postdoctoral Fellow Institution: Newcastle University Department: School of engineering Address: Merz Court, Claremont Road  Newcastle upon Tyne  NE1 7RU  NEWCASTLE UPON TYNE, Tyne and Wear  United Kingdom, NE17RU

Email: Not public
Telephone: +447747702682
Cell: +447747702682

Social media and scholarly resources
Twitter: https://twitter.com/@evopankaj
Facebook: https://www.facebook.com/pankaj.singla.35
LinkedIn: https://www.linkedin.com/in/dr-pankaj-singla-507b74ab/
ORCID: https://orcid.org/ 0000-0001-6999-1744
Google Scholar: https://scholar.google.com/https://scholar.google.co.in/citations?user=YM2QVIsAAAAJ&hl=en
Researchgate: https://www.researchgate.net/profile/Pankaj-Singla-5

Personal statement:
I am Pankaj Singla, currently working as Marrie Curie Postdoctoral Fellow in Newcastle University, UK. I completed my PhD from Guru Nanak Dev University, Amritsar, India and my research work focused on the delivery of hydrophobic drugs with polymeric and surface active molecules. Extending my research work, I am now working on the novel molecular imprinted nanoparticles for the drug delivery as well as drug candidates itself. Protein-Protein intractions (PPI) plays a major role in cellular signaling pathways, by targeting extracellular proteins present on the cell membranes, one can target these proteins for multiple applications. Nowdays, I am synthesizing novel molecular imprinted polymeric nanoparticles (nanoMIPs) for the estrogen positive breast cancer cells by employing solid phase synthesis. To synthesize cost effective nanoMIPs for cancer therapeutics, one can use epitope (small peptide sequence) rather than whole protein. So, I imprint both epitope (for example: epitope for estrogen alpha receptor) and anti-cancer drug simultaneously to achieve targeted drug delivery. I am also looking whether with these nanoparticels, can we stop the protein-protein intractions responsible for the cancer survival and progression.